Welcome to RiboEdge Biotech

We're building Africa’s first RNA therapeutics company focused on neglected viral diseases like Crimean-Congo Hemorrhagic Fever. With a precision-based siRNA platform and a mission rooted in the continent’s public health needs, RiboEdge Biotech is rewriting the future of antiviral drug discovery.

🧬 Our Science

The Problem

Viral hemorrhagic fevers like CCHFV are a growing threat in Africa yet remain virtually ignored in global drug pipelines. They are dangerous, fast-moving, and often lethal. Current control measures rely on outdated tools, vector management, isolation, and hope.

Our Approach

We are developing small interfering RNA (siRNA) therapeutics that silence key viral genes essential to replication and immune evasion. Using computational tools and African-centric genomic data, we identify optimal gene targets, design high-potency siRNA sequences, and simulate their interactions in silico.

Our pipeline begins with:

  • L segment target disruption: Blocking RNA polymerase synthesis

  • S segment interference: Silencing nucleoprotein assembly

  • Future steps include nanoparticle delivery, in vitro screening, and partnerships for scale-up.

Our Advantage

By combining:

  • Disease-specific African data

  • Computational bioinformatics

  • RNAi therapeutic design

We are creating scalable, smart, and responsive antivirals tailored to emerging and re-emerging viruses often neglected by big pharma.

🔭 What’s Next

We are currently in the proof-of-concept phase of our lead siRNA candidates targeting the CCHFV genome. Our immediate priorities include:

  • In silico validation of RNAi constructs

  • Building research collaborations across South Africa

  • Seeking access to BSL-3/4 labs for experimental validation

  • Engaging investors, advisors, and partners to expand our scientific and operational footprint

The path is long but the science is sound, and the mission is urgent.

About us

RiboEdge Biotech is a leading biotechnology company based in Johannesburg, South Africa. Our team of experts is dedicated to driving innovation and excellence in the field of biotechnology, offering a wide range of services to meet the needs of our clients.